ROLE OF XENOBIOTIC DETOXIFICATION GENE POLYMORPHISM DURING DRUG THERAPY OF THREATENED ABORTION

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Issue: 
5
Year: 
2016

Professor O. Makarov (1), MD; S. Lunina (1); L. Salnikova (2), Biol. Dr; V. Goncharova (1) 1 -N.I. Pirogov Russian National Research Medical University, Moscow 2 -N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow

Individual drug sensitivity that is largely determined by the polymorphism of genes encoding the enzymes metabolizing this drug remains one of the main causes of the high incidence of poor outcomes of pregnancy.
Keywords: 
miscarriage
xenobiotic detoxification gene polymorphisms
pharmacokinetics
pharmacogenetics
prevention of miscarriage

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