THE XENOBIOTIC DETOXIFICATION SYSTEM IN THE THERAPY OF THREATENED ABORTION

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Issue: 
4
Year: 
2016

Professor O. Makarov (1), MD; S. Lunina (1); L. Salnikova (2), Biol. D; N. Lutsenko (1); V. Goncharova (1) 1 -N.I. Pirogov Russian National Research Medical University, Moscow 2 -N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow

Despite performed therapy for abortion, the highest risk of miscarriage was associated with a combination of the risky alleles of the ABCB1 and GSTP1 genes; the frequency of this combination was 13.2%.
Keywords: 
obstetrics and gynecology
miscarriage
xenobiotic detoxification gene polymorphisms
GSTP1
ABCB1
results of therapy

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