FIBROGENESIS AS AN OBJECT OF PHARMACOLOGICAL REGULATION: ALTERNATIVE ABILITIES OF SLOW-RELEASE CALCIUM CHANNEL BLOCKERS

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Issue: 
4
Year: 
2016

S. Skalsky (1), Candidate of Medical Sciences; Professor D. Sychev (2), MD 1 -Omsk State Medical University 2 -Russian Medical Academy of Postgraduate Education, Moscow

The paper discusses whether slow-release calcium channel blockers (SCCBs) may be used to regulate the processes of connective tissue formation. The main pathogenetic components of fibrogenesis, which determine the expediency of the administration and efficiency of SCCBs, are defined. The authors give the results of their own studies of the antifibrotic effect of verapamil.
Keywords: 
pharmacology
fibrosis
antifibrotic therapy
calcium channel blockers

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