EXPERIENCE IN RECORDING UNDESIRABLE SIDE EFFECTS FROM ANTIEPILEPTIC DRUGS IN THE KRASNOYARSK MEDICAL UNIVERSITY CLINIC

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Issue: 
4
Year: 
2016

E. Bochanova, Candidate of Medical Sciences; N. Shnaider, MD; D. Dmitrenko, MD; E. Shapovalova, Candidate of Medical Sciences; O. Veselova, Candidate of Medical Sciences; O. Shilkina; T. Potupchik, Candidate of Medical Sciences Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

The paper describes some experience in recording adverse reactions to antiepileptic drugs. To train physicians in pharmacovigilance, to include information on undesirable side effects from the drugs into the structure of a clinical diagnosis, and to comply with the current pharmacovigilance legislative requirements increase the detection rates of side effects from the drugs.
Keywords: 
pharmacology
epilepsy
adverse side effects from drugs

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References: 
  1. Algoritm vzaimodejstvija uchastnikov sistemy Farmakonadzora po vyjavleniju i rabote so spontannymi soobschenijami. Metodicheskie rekomen-datsii. Utv. rukovoditelem Federal'noj sluzhby po nadzoru v sfere zdravo-ohranenija i sotsial'nogo razvitija N.V. Jurgelem 22.10.2009.
  2. Andreeva O.V. Primenenie terapevticheskogo lekarstvennogo monitorin finlepsina v krovi v klinicheskoj praktike // Klin. farmakokinetika. – 2005; 1 (2): 29–33.
  3. Astahova A.V., Lepahin V.K. Farmakoekonomicheskie aspekty pobochnyh effektov i oslozhnenij lekarstvennoj terapii // Zamestitel' glavnogo vracha. – 2009; 7: 7–13.
  4. Bochanova E.N., Veselova O.F., Shnajder N.A. i dr. Otsenka chastoty off lejbl vypisyvanija preparatov dlja detej, bol'nyh epilepsiej. Materialy V Jubilejnogo Baltijskogo kongressa po detskoj nevrologii / SPb: Chelovek i ego zdorov'e, 2015; s. 68.
  5. Dmitrenko D.V., Shnajder N.A., Shapovalova E.A. i dr. Farmakogeneticheskie osobennosti metabolizma preparatov val'proevoj kisloty: ucheb. posobie / Krasnojarsk: Operativnaja poligrafija, 2015; 75 s.
  6. Monitoring bezopasnosti lekarstvennyh preparatov v voprosah i otvetah: Broshjura dlja spetsialistov zdravoohranenija. URL: http://www.roszdravnadzor.ru/i/upload/images/2014/12/2/1417522012.38688-1-10261.pdf (data obraschenija: 28.03.2016).
  7. Pis'mo Federal'noj sluzhby v sfere zdravoohranenija i sotsial'nogo razvitija (Roszdravnadzor) ot 12.11.2014 №01I-1789/14 «O monitoringe bezopasnosti lekarstvennyh preparatov».
  8. Pis'mo Federal'noj sluzhby v sfere zdravoohranenija i sotsial'nogo razvitija (Roszdravnadzor) ot 11.04.2012 №04I-266/12 «O srochnom predo-stavlenii svedenij o letal'nyh nezhelatel'nyh reaktsijah na lekarstvennye preparaty».
  9. Prikaz MZ i SR ot 26.08.2010 №757n «Ob utverzhdenii porjadka osu schestvlenija monitoringa bezopasnosti lekarstvennyh preparatov dlja medi-tsinskogo primenenija, registratsii pobochnyh dejstvij, ser'eznyh nezhela-tel'nyh reaktsij, nepredvidennyh nezhelatel'nyh reaktsij pri primenenii lekarstvennyh preparatov dlja meditsinskogo primenenija». Federal'nyj zakon ot 12.04.2010 №61-FZ «Ob obraschenii lekar stvennyh sredstv» (red. ot 29.12.2015).
  10. Shnajder N.A., Bochanova E.N., Zyrjanov S.K. i dr. Ispol'zovanie regi stra patsientov s epilepsiej i epilepticheskimi sindromami dlja analiza pobochnyh effektov protivoepilepticheskih preparatov // Sovremennye pro-blemy nauki i obrazovanija. – 2016; 2. URL: http://www.science-education.ru/article/view?id=24254 (data obraschenija: 28.03.2016).
  11. Shnajder N.A., Piljugina M.S., Dmitrenko D.V. i dr. Chastota vstre-12. chaemosti nezhelatel'nyh lekarstvennyh reaktsij na fone priema antikon-vul'santov u bol'nyh epilepsiej // Klin. farmakol. i terapija. – 2010; 6: 180–4
  12. Shnajder N.A., Piljugina M.S., Dmitrenko D.V. Stratifikatsija epilepsiej po gruppam riska razvitija nezhelatel'nyh lekarstvennyh javlenij na fone priema preparatov val'proevoj kisloty // Zamestitel' glavnogo vracha. – 2011; 7: 50–61.