INTERGENIC INTERACTIONS IN THE DEVELOPMENT OF SILENT MYOCARDIAL ISCHEMIA

Download full text PDF
Issue: 
9
Year: 
2015

M. Khabibulina, Candidate of Medical Sciences Ural State Medical University, Yekaterinburg

A study of a differently marked genetic component of the above-mentioned disease is a promising method in identifying a risk for cardiovascular diseases and in predicting their outcomes.
Keywords: 
gene polymorphisms
estrogen deficiency
silent myocardial ischemia

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Gallagher P., John P. Estrogen regulation of angiotensin-converting enzyme mRNA // Hypertension. – 1999; 33: 323–8.
  2. Tereschenko S.N. Polimorfizm genov angiotenzinprevraschajuschego fermenta, angiotenzina II, NO-sintetazy, estrogenovyh retseptorov i gendernye razlichija v ih vlijanii na razvitie serdechno-sosudistoj patologii // Kardiologija. – 2009; 4: 58–62.
  3. Le Corvoiser P., Park H. Modifier genes and heart failure // Minerva Cardioangiol. – 2003; 51: 107–20.
  4. Zhu H., Wang X. Influence of eNOS gene on development of blood pressure and left ventricular mass // Pharmacogenet. Genomics. – 2005; 9: 669–75.
  5. Casas P. Gene polymorphisms and cardiovascular disease-A HuGE Review // Am. J. Epidemiol. – 2006; 10: 921–35.
  6. Koch W., Schrempf M., Erl A. et al. 4G/5G polymorphism and haplotypes of SERPINE 1 in atheroscherotic diseases of coronary arteries // Thromb. Haemost. – 2010; 103 (6): 1170–801.
  7. Gardemann A. Angiotensin 2 type 1 receptor A 1166C gene polymorphism // Eur. Heart J. – 1998; 11: 1657–65.
  8. Zatejschikov D.A., Minushkina L.O. Novye issledovanija polimorfizma gena retseptora angiotenzina II 1-go tipa i gemostaza u lits s IBS // Klin. gomostaziologija. – 2003; 4: 12–7.
  9. Tselujko V.I. Polimorfizm gena APF u bol'nyh s gipertroficheskoj kardiomiopatiej // Ukrainskij kardiol. zhurn. – 2000; 3: 37–41.
  10. Melent'ev I.A. Klinicheskoe techenie IBS, postinfarktnoe remodelirovanie, psihologicheskij status, sroki gospitalizatsii bol'nyh s raznymi genotipami gena APF // Ros. kardiol. zhurn. – 2006; 3: 62–9
  11. Tereschenko S.N., Demidova I.V. Strukturno-funktsional'noe sostojanie LZh i effektivnost' iAPF perindoprila u bol'nyh s postinfarktnoj SN v zavisimosti ot gena APF // Kardiologija. – 2000; 1: 34–7.
  12. Hentonen A. Estrogen receptor 1 genotype is related to coronary intima thickness in young to middle-aged women // Scand. J. Clin. Lab. Invest. – 2007; 67: 380–6.
  13. Figtree G., Lind L. Novel estrogen receptor α promoter polymorphism increases ventricular hypertrophic response to hypertension // J. Steroid. Biochem. Mol. Biol. – 2007; 2: 110–8.
  14. Shearman A. Association between estrogen receptor α gene variation and cardiovasculardisease // JAMA. – 2003; 17: 2263–70.
  15. Herrington D. Role of estrogen receptor α in pharmacogenetics of estrogen action // Curr. Opin. Lipidol. – 2003; 2: 145–50