Эффективность венлафаксина при хроническом болевом синдроме

DOI: https://doi.org/10.29296/25877305-2019-04-06
Номер журнала: 
4
Год издания: 
2019

Т. Вазагаева, кандидат медицинских наук, Э. Кварианташвили Национальный медицинский исследовательский центр психиатрии и наркологии им. В.П. Сербского, Москва E-mail: vazagaeva@mail.ru

В настоящее время при лечении различных хронических болевых синдромов наряду с анальгетиками рекомендуется применять адъювантные препараты. К числу антидепрессантов с доказанным анальгетическим действием относится венлафаксин, обладающий более благоприятным профилем переносимости, чем трициклические антидепрессанты, традиционно используемые при лечении пациентов с хронической болью (ХБ). Во многих исследованиях показана высокая эффективность венлафаксина при терапии нейропатической боли, в то время как эффективность препарата при других видах ХБ изучена недостаточно. Хотя в большинстве современных руководств венлафаксин не рассматривается в качестве препарата 1-й линии при лечении ХБ, имеются основания для его применения в клинической практике во многих случаях, например при плохой переносимости или наличии противопоказаний к приему других антидепрессантов и противосудорожных препаратов. Для расширения и дополнения сведений об особенностях и спектре анальгетической активности венлафаксина необходимы дальнейшие исследования.
Ключевые слова: 
терапия, хронический болевой синдром, Венлафаксин

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