CARDIORESPIRATORY DISORDERS, CYTOKINE IMBALANCE, AND COGNITIVE DYSFUNCTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE CONCURRENT WITH HYPERTENSIVE DISEASE IN THE PRESENCE OF OBESITY

DOI: https://doi.org/10.29296/25877305-2018-04-01
Download full text PDF
Issue: 
4
Year: 
2018

Professor T. Vasilkova, MD; Yu. Rybina; Professor V. Kolpakov, MD Tyumen State Medical University

The paper shows the role of obesity in the progression of comorbid cardiorespiratory disease and in the increased risk of not only cardiopulmonary catastrophes, but also serious mental disorders up to severe dementia.

Keywords: 
pulmonology
neurology
endocrinology
chronic obstructive pulmonary disease
hypertensive disease
cardiorespiratory disorders
cytokine imbalance
obesity



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Astaf'eva N.G., Gamova I.V. i dr. Ozhirenie i bronhial'naja astma // Lechaschij vrach. – 2014; 4: 8–13.
  2. Bondarenko V.M., Marchuk V.P., Pimanov S.I. i dr. Korreljatsija soderzhanija vistseral'noj zhirovoj tkani po dannym komp'juternoj tomografii s antropometricheskimi pokazateljami i rezul'tatami ul'trazvukovogo issledovanija // Vestn. Vitebskogo gosudarstvennogo meditsinskogo universiteta. – 2013; 1: 31–8.
  3. Vasil'kova T.N., Baklaeva T.B., Mataev S.I. i dr. Rol' ozhirenija v formirovanii serdechno-sosudistoj patologii // Prakt. meditsina. – 2013; 7: 117–22.
  4. Vasil'kova T.N. Klinicheskie osobennosti i patogeneticheskie mehanizmy progressirovanija hronicheskoj obstruktivnoj bolezni legkih na fone ozhirenija // Meditsinskaja nauka i obrazovanie Urala. – 2008; 4: 8–10.
  5. Efimov N.Ju., Chernov V.I., Efimova I.Ju. i dr. Rol' disfunktsii endotelija v mehanizme razvitija kognitivnyh narushenij u patsientov s metabolicheskim sindromom // Sib. vestn. psihiat. i narkol. – 2010; 2 (59): 5–89.
  6. Matveeva M.V., Samojlova Ju.G., Zhukova N.G. Ozhirenie i kognitivnaja disfunktsija // Ozhirenie i metabolizm. – 2016; 13 (3): 3–8.
  7. Tanashjan M.M., Lagoda O.V., Orlov S.V. i dr. Sosudistye zabolevanija golovnogo mozga i metabolicheskij sindrom // Ter. arh. – 2013; 85 (10): 32–4.
  8. Chuchalin A.G. Hronicheskaja obstruktivnaja bolezn' legkih i soputstvujuschie zabolevanija // Ter. arh. – 2008; 8: 45–50.
  9. Chu N., Spiegelman D., Hotamisligil G. et al. Plasma insulin, leptin, and soluble TNF receptoirs levels in relation to obesity related atherogenic and thrombogenic cardiovascular disease risk factors among men // Atherosderosis. – 2001; 157: 495–503.
  10. Hajer G., van Haeften T., Visseren F. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases // Eur. Heart J. – 2008; 29: 2959–71.
  11. Lloyd-Jones D., Adams R., Brown T. et al. Executive summary: heart disease and stroke statistics – 2010 update: A report from the American Heart Association // Circulation. – 2010; 121 (7): e46–e215.
  12. Miller A., Spencer S. Obesity and neuroinflammation: A pathway to cognitive impairment // Brain Behav. Immun. – 2014; 42: 10–21. DOI:10.1016/j.bbi.2014.04.001.
  13. Puig J., Blasco G., Daunis-Estadella J. et al. Hypothalamic Damage Is Associated With Inflammatory Markers and Worse Cognitive Performance in Obese Subjects // J. Clin. Endocrinol. Metab. – 2015; 100 (2): E276–81. DOI: 10.1210/jc.2014-2682.