SUCCESSFUL COMBINED TREATMENT FOR HYPERTENSIVE LEG ULCERS (MARTORELL’S ULCERS)

DOI: https://doi.org/10.29296/25877305-2018-02-14
Download full text PDF
Issue: 
2
Year: 
2018

Professor N. Vatutin (1, 2), MD; Professor E. Fistal (1, 2), MD; G. Taradin (1, 2), Candidate of Medical Sciences; Professor I. Vasilenko (1), MD; I. Grishchenko (2); M. Goncharuk (1) 1-M. Gorky Donetsk National Medical University, Donetsk, Ukraine 2-V.K. Gusak Institute of Emergency and Restorative Surgery, Donetsk

The paper describes a case of development of hypertensive leg ulcers (Martorell’s ulcers) in a male patient who has been suffering from essential hypertension for many years. Wound healing could be achieved after selecting antihypertensive therapy and performing a stepwise dermatoplasty. The paper provides a brief review of the literature.

Keywords: 
surgery
Martorell’s ulcers
hypertension



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Aralova M.V., Gluhov A.A. Klinicheskij sluchaj lechenija patsientki s jazvoj Martorella // Vestn. eksperim. i klin. hirurgii. – 2014; 7 (3): 265–8.
  2. Hafner J., Nobbe S., Partsch H. et al. Martorell hypertensive ischemic leg ulcer: a model of ischemic subcutaneous arteriolosclerosis // Arch. Dermatol. – 2010; 146 (9): 961–8.
  3. Haxthausen H. Arteriosclerotic ulcers of the leg // Nord Med. – 1940; 8: 1663–5.
  4. Martorell F. Las ulceros supramaleolares por arteriolitis de las grandes hipertensas // Acta Inst. Policlinico Barcelona. – 1945; 1: 6–9.
  5. Hines E., Farber E. Ulcer of the leg due to arteriosclerosis and ischaemia occurring in the presence of hypertensive disease (hypertensive ischaemic ulcers): a preliminary report // Proceedings of the Staff Meetings of the Mayo Clinic. – 1946; 21: 337–46.
  6. Schnier B., Sheps S., Juergens J. Hypertensive ischemic ulcer: a review of 40 cases // Am. J. Cardiol. – 1966; 17 (4): 560–5.
  7. Lazareth I., Priollet P. Necrotic angiodermatitis: treatment by early cutaneous grafts [in French] // Ann. Dermatol. Venereol. – 1995; 122 (9): 575–8.
  8. Henderson C., Highet A., Lane S. et al. Arterial hypertension causing leg ulcers // Clin. Exp. Dermatol. – 1995; 20 (2): 107–14.
  9. Alavi A., Mayer D., Hafner J. et al. Martorell hypertensive ischemic leg ulcer: an underdiagnosed Entity© // Adv. Skin Wound Care. – 2012; 25 (12): 563–72.
  10. Shutler S., Baragwanath P., Harding K. Martorell’s ulcer // Postgrad. Med. J. – 1995; 71: 717–9.
  11. Vuerstaek J., Reeder S., Henquet C. et al. Arteriolosclerotic ulcer of Martorell // J. Eur. Acad. Dermatol. Venereol. – 2010; 24 (8): 867–74.
  12. Leu H. Hypertensive ischemic leg ulcer (Martorell’s ulcer): a specific disease entity? // Int. Angiol. – 1992; 11: 132–6.
  13. Allen E., Barker N., Hines E. Peripheral Vascular Diseases. 3rd eds. / Philadelphia: WB Saunders, 1962; p. 534–42.
  14. Martorell F. Ulcera hipertensiva extensa. Tratamiento par la simpatectomia lumbar y el inyerto cutaneo (Presentación de 2 casos) // Angiologia. – 1962; 14: 194.
  15. Khouri V., Bueno Neto J., Puech Leāo L. et al. As ulceras isquemicas hipertensivas e seu tratamento pela simpatectomia // Rev. Paul Med.– 1964; 65: 187.
  16. Beccaria A., Troncone S. La nostra esperienza sulla terapia dell’ulcera ipertensiva (sindrome di Martorell) // Minerva Chir. – 1965; 20: 764–7.
  17. Coppi G., Catellani C., Silingardi R. et al. La nostra esperienza nella terapia dell’ulcera ipertensiva di Martorell // Minerva Chir. – 1983; 38: 1585–7.
  18. Bertranou E., Gonoraky S., Otero A. Ulcere arteriolaire hypertensif de Martorell: resultat de traitement ambulatoire sur 366 cas // Phlébologie. – 2001; 54: 267–72.
  19. Dagregorio G., Guillet G. A retrospective review of 20 hypertensive leg ulcers treated with mesh skin grafts // JEADV. – 2006; 20: 166–9.
  20. Alberdi J. Hypertensive ulcer: Martorell's ulcer // Plaelebology.– 1988; 5: 139–42.
  21. Kuiper J., Brakkee A. Hautdurchblutungsmessing bei mikroangiopathischen Veranderungen // Z Hautkr. – 1985; 60: 1495–505.
  22. Freire B., Fernandes N., Piñeiro-Maceira J. Martorell's hypertensive ulcer: case report // An. Bras. Dermatol. – 2006; 81 (5 Supl. 3): 327–31.
  23. Khouri C., Jouve T., Blaise S. et al. Peripheral vasoconstriction induced by β-adrenoceptor blockers: a systematic review and a network meta-analysis // Br. J. Clin. Pharmacol. – 2016; 82 (2): 549–60.
  24. Graves J., Morris J., Sheps S. Martorell's hypertensive leg ulcer: case report and concise review of the literature // J. Hum. Hypertens. – 2001; 15 (4): 279–83.
  25. Boggio R., Freitas V., Cassiola F. et al. Effect of a calcium-channel blocker (verapamil) on the morphology, cytoskeleton and collagenase activity of human skin fibroblasts // Burns. – 2011; 37 (4): 616–25.
  26. Ramos-Gallardo G., Miranda-Altamirano A., Valdes-López R. et al. Verapamil in conjunction with pressure therapy in the treatment of pathologic scar due burn injury // Rev. Med. Inst. Mex. Seguro Soc. – 2016; 54 (4): 454–7.
  27. Nikolova K. Treatment of hypertensive venous leg ulcers with nifedipine // Meth. Find Exp. Clin. Pharmacol. – 1995; 17: 545–9.
  28. Malhi H., Didan A., Ponosh S. et al. Painful leg ulceration in a poorly controlled hypertensive patient: a case report of Martorell ulcer // Case Rep. Dermatol. – 2017; 9 (1): 95–102.
  29. Pinto A., Silva N. Jr., Osorio C. et al. Martorell's ulcer: diagnostic and therapeutic challenge // Case Rep. Dermatol. – 2015; 7 (2): 199–206.