The importance of metabolic markers in the development of a second ischemic stroke

DOI: https://doi.org/10.29296/25877305-2020-10-12
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Issue: 
10
Year: 
2020

V. Shishkova(1, 2), Candidate of Medical Sciences; Professor T. Adasheva(2), MD; Professor L.
Stakhovskaya(3), MD (1)Center for Speech Pathology and Neurorehabilitation, Moscow Healthcare Department
(2)A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia (3)N.I.
Pirogov Russian National Research Medical University, Moscow

Objective. To investigate the relationship between plasma adiponectin (ADN) levels and the rate of a second noncardioembolic ischemic stroke (IS) over a three-year period Subjects and methods. The cohort observational study covered 206 patients who had experienced a first noncardioembolic IS, explored the clinical and metabolic parameters of the participants, and assessed the frequency and date of onset of a secondary IS using the Cutler-Ederer and Kaplan-Meier methods according to AND concentrations. Fasting plasma ADN concentrations (μg/ml) were determined using the BioVendor kits (Sweden) on a third-generation Reader UNIPLAN-9213 microplate photometer (PIKON, Russia). Results. The analysis of the frequency and date of onset of a second noncardioembolic IS over a three-year period showed an increased risk of its development in patients with low ADN levels (
Keywords: 
neurology
endocrinology
ischemic stroke
adiponectin
second stroke

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