Prevalence of sarcopenia in cardiac inpatients

DOI: https://doi.org/10.29296/25877305-2020-09-13
Download full text PDF
Issue: 
9
Year: 
2020

M. Kaleichik(1); T. Bolshakova(1), Candidate of Medical Sciences; E. Kapustina(1, 2), Candidate
of Medical Sciences; V. Chupakhina(1), Candidate of Medical Sciences; T. Potupchik(1), Candidate of Medical
Sciences (1)Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University (2)Territorial Clinical
Hospital, Krasnoyarsk

Patients of older age groups have high comorbidity. Among geriatric diseases, sarcopenia that is a risk factor for adverse outcomes attracts increasing attention. Objective: to study the incidence of sarcopenia in persons over 60 years of age who have been admitted to a cardiology department. Subjects and methods. Thirty-six elderly and 64 senile patients were diagnosed with sarcopenia according to the updated EWGSOP2 guidelines (2018). After screening with the SARC-F questionnaire, all the patients at risk of sarcopenia underwent muscle strength measurement using a handheld dynamometer and the chair stand test, the muscle function assessment using the Short Physical Performance Battery (SPPB), as well as muscle mass estimation by bioimpedence. Results. There was a risk of sarcopenia in 78 (78%) persons [elderly (n=21) and senile (n=57) ones]. There was a decline in muscle strength, muscle function, and muscle mass in 64%, 55%, and 60% of the patients, respectively. Sarcopenia was diagnosed in 53% of the patients (42% in women and 11% in men); severe sarcopenia was identified in 49%. Sarcopenia was detected in 19.4% of elderly cases and in 71.9% of senile ones. In 100% of the senile women, the SARC-F scores coincided with the results obtained by other sarcopenia diagnostic techniques. Conclusion. Sarcopenia is a common comorbidity in patients with cardiovascular diseases. The rate of sarcopenia in elderly and senile cardiac patients is 53%, substantially increasing with age; severe sarcopenia was diagnosed in 49% of cases. Sarcopenia is detected much more common in women than in men. The SARC-F questionnaire to screen sarcopenia is highly predictable, especially in elderly women.

Keywords: 
sarcopenia
geriatrics
comorbidity
muscle strength
dynamometry



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Bogat S.V. Rasprostranennost' sarkopenii u patsientov starshih vozrastnyh grupp. Gerontologija. 2014; 2 (3): 305–10 [Bogat S.V. Prevalence of sarcopenia in patients over age group. Gerontology. 2014; 2 (3): 305–10 (in Russ.)].
  2. Mokrysheva N.G., Krupinova Ju.A., Volodicheva V.L. i dr. Sarkopenija galazami endokrinologa. Ozhirenie i metabolizm. 2018; 15 (3): 21–7 [Mokrysheva N.G., Kropinova J.A., Volodicheva V.L. et al. Sarcopenia eyes endocrinologist. Obesity and metabolism. 2018; 15 (3): 21–7 (in Russ.)]. https://doi.org/10.14341/OMET9792
  3. Naumova L.A., Osipova O.N. Komorbidnost': mehanizmy patogeneza, klinicheskoe znachenie. Sovremennye problemy nauki i obrazovanija. 2016; 5: 105 [Naumova L. A., Osipova O. N. Comorbidity: mechanisms of pathogenesis, clinical significance. Modern problems of science and education. 2016; 5: 105 (in Russ.)]. URL: http://science-education.ru/ru/article/view?id=25301
  4. Nikolaev, D.V., Schelykalina S.P. Lektsii po bioimpedansnomu analizu sostava tela cheloveka. M.: RIO TsNIIOIZ MZ RF, 2016 [Nikolaev, D.V., Selegaline S.P. Lectures on bioimpedance analysis of the composition of the human body. M.: RIO TSNIIOIZ, 2016 (in Russ.)].
  5. Noskov S.N., Zavodchikov A.A., Lavruhina A.A., i dr. Klinicheskoe znachenie sarkopenii i miopenii. Klinicheskaja gerontologija. 2015; 5–6: 46–50 [Noskov S.N., Zavodchikov A.A., Lavrukhina A.A. et al. Clinical significance of sarcopenia and myopenia. Clinical gerontology. 2015; 5–6: 46–50 (in Russ.)].
  6. Plaksin N.S., Bogdanova T.M. Komorbidnost' zabolevanij serdechno-sosudistoj sistemy pri hronicheskoj bolezni pochek. Mezhdunarodnyj studencheskij nauchnyj vestnik. 2018; 5: 66 [Plaksin N.S., Bogdanova T.M. Comorbidity of cardiovascular diseases in chronic kidney disease. International student scientific bulletin. 2018; 5: 66 (in Russ.)]. URL: http://eduherald.ru/ru/article/view?id=19188
  7. Safronova Ju.A., Zotkin E.G. Sarkopenija u patsientok starshego vozrasta s osteoartritom krupnyh sustavov. Nauchno-prakticheskaja revmatologija. 2019; 57 (2): 154–9 [Safronova U.A., Zotkin E.G. Sarcopenia in patients older with osteoarthritis of large joints. Rheumatology Science and Practice. 2019; 57 (2): 154–9 (in Russ.)]. https://doi.org/10.14412/1995-4484-2019-154-159
  8. Sindeeva L.V., Kazakova G.N. Vozmozhnost' ispol'zovanija parametrov bioimpedansometrii dlja rascheta kostnoj massy v antropologicheskih issledovanijah (na primere zhenskogo naselenija Vostochnoj Sibiri). Sovremennye problemy nauki i obrazovanija. 2013; 4: 123 [Sindeeva L.V., Kazakova G.N. Possibility of use of the bioimpedansometric parameters for calculation of bone mass in anthropological researches (on the example of the female population in Eastern Siberia). Modern problems of science and education. 2013; 4: 123 (in Russ.)]. URL: http://www.science-education.ru/pdf/2013/4/177.pdf
  9. Sindeeva L.V., Sharajkina E.N., Zhavnerovich L.M. Harakteristika zhirovogo komponenta somy muzhchin v zavisimosti ot vozrasta. Aktual'nye voprosy integrativnoj antropologii: sb. nauch. tr. Krasnojarsk, 2001; 2: 163–6 [Sindeeva L.V., Saraikin E.N., Gavrilovic L.M. Characteristics of the fat component of soma men depending on age. Topical issues of integrative anthropology. Krasnoyarsk, 2001; 2: 163–6 (in Russ.)].
  10. Turusheva A.V, Frolova E.V., Degriz Ja.-M. Raschet vozrastnyh norm rezul'tatov kistevoj dinamometrii dlja zdorovyh ljudej starshe 65 let v Severo-Zapadnom regione Rossii: rezul'taty prospektivnogo kogortnogo issledovanija «Hrustal'». Rossijskij semejnyj vrach. 2017; 21 (4): 29–35 [Turusheva A.V., Frolova E.V., Degrize J.-M. Development of reference ranges of handgrip strength among healthy adults 65+ in northwest Russia: a prospective population-based cohort CRYSTAL study. Russian Family Doctor. 2017; 21 (4): 29–35 (in Russ.)]. https://doi.org/10.17816/RFD2017429-35
  11. Anker S.D., Morley J.E., von Haehling S. Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia Muscle. 2016; 7 (5): 512–4. https://doi.org/10.1002/jcsm.12147
  12. Collamati A., Marzetti E., Calvani R. et al. Sarcopenia in heart failure: mechanisms and therapeutic strategies. J Geriatr Cardiol. 2016; 13 (7): 615–24. DOI: 10.11909/j.issn.1671-5411.2016.07.004
  13. Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M. et al. Sarcopenia: European consensus on definition and diagnosis: report of the working group on sarcopenia in older people. Age Ageing. 2010; 39 (4): 412–23. DOI: 10.1093/ageing/afq034
  14. Cruz-Jentoft A.J., Bahat G., Bauer J. et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019; 48 (1): 16–31. DOI: 10.1093/ageing/afy169
  15. Curtis J.P., Seiter J.G., Wang Y. et al. The obesity paradox: body mass index and outcomes in patients with heart failure. Arch Intern Med. 2005; 165: 55–61. DOI: 10.1001/archinte.165.1.55
  16. Kapoor J.R., Heidenreich P.A. Obesity and survival in patients with heart failure and preserved systolic function: a U-shaped relationship. Am Heart J. 2010; 159 (1): 75–80. DOI: 10.1016/j.ahj.2009.10.026
  17. Kenchaiah S., Pocock S.J., Wang D. et al. Body mass index and prognosis in patients with chronic heart failure: insights from the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) program. Circulation. 2007; 116: 627–36. http://dx.doi.org/10.1161/CIRCULATIONAHA.106.679779