Metabolic changes in the skin during aging and their correction methods

DOI: https://doi.org/10.29296/25877305-2020-09-03
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Issue: 
9
Year: 
2020

O. Kapuler, MD ZAO «Cosmetology Clinic», Ufa

The external signs of skin aging are associated with a reduction in the number and functional activity of cells, with changes in metabolic rate, and with degradation of the main components of the extracellular matrix, first of all, the dermal collagen framework, as well as proteoglycans and hyaluronan. Understanding the metabolic processes and physiological mechanisms that occur in the skin during aging is the fundamental basis for the development of different methods for correcting involutional changes; however, the adequacy of their choice should be dictated by the etiopathogenetic validity, effect predictability, and use comforts.
Keywords: 
dermatology
collagen
hyaluronic acid
aging
skin
fibroblasts

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