Features of the course of community-acquired pneumonias in women of childbearing age
DOI: https://doi.org/10.29296/25877305-2020-08-08
Issue:
8
Year:
2020
In recent years, the results of a number of studies have been published, suggesting the more severe
course of community-acquired pneumonias in the gestation period. The data on the course of pneumonia in
pregnant women during the COVID-19 pandemic are also extremely relevant. Objective: to compare the features
of diagnosis, course, and treatment of community-acquired pneumonia in women of childbearing age in the
presence and absence of pregnancy. Subjects and methods. Case histories were used to comparatively analyze
the course and treatment of community-acquired pneumonia in women of childbearing age during pregnancy (n =
35) and non-gestation (n = 28). There are also data on the specific features of the course of COVID-19
during pregnancy. Results. Most (70%) pregnant women were hospitalized in the second trimester. During
pregnancy, hospitalization was carried out in a significantly shorter time. On hospital admission, the
number of patients with moderate disease was significantly higher, whereas saturation was significantly
lower in the group of pregnant women; however, both groups showed mild symptoms represented by fever, cough
that was mostly dry. The content of stab neutrophils was significantly higher in the group of pregnant
patients. In both groups, initial antibacterial therapy was significantly more frequently performed with
intravenous ceftriaxone than with other drugs. The duration of hospitalization did not differ in the groups
and averaged 12 days. Conclusion. Based on the findings, the authors cannot conclude that there are
substantial differences in the severity of the course and symptoms and in the duration of treatment for
community-acquired pneumonia in pregnant women and women of childbearing age during the non-gestation
period.
Keywords:
obstetrics and gynecology
infectious diseases
community-acquired pneumonia
pregnancy
childbearing age
treatment
COVID-19
References:
- Sinopal'nikov A.I., Fesenko O.V. Vnebol'nichnaja pnevmonija. M.: GEOTAR-Media, 2017; 112 s. [Sinopal’nikov A.I., Fesenko O.V. Vnebol’nichnaya pnevmoniya. M.: GEOTAR-Media, 2017; 112 s. (in Russ.)]. Dostupno na: Available at: https://www.rosmedlib.ru/book/ISBN9785970442890.html
- Mehta N., Chen K., Hardy E. et al. Pneumonia in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2015; 29 (5): 598–611. DOI: 10.1016/j.bpobgyn.2015.04.005
- Romanyuk V., Raichel L., Sergienko R. et al. Pneumonia during pregnancy: radiological characteristics, predisposing factors and pregnancy outcomes. J Matern Fetal Neonatal Med. 2011; 24 (1): 113–7. DOI: 10.3109/14767051003678275
- Starshinova A.A., Kushnareva E.A., Malkova A.M. i dr. Novaja koronavirusnaja infektsija: osobennosti klinicheskogo techenija, vozmozhnosti diagnostiki, lechenija i profilaktiki infektsii u vzroslyh i detej. Voprosy sovremennoj pediatrii. 2020; 19 (2): 123–31 [Starshinova A.A., Kushnareva E.A., Malkova A.M. et al. New Coronaviral Infection: Features of Clinical Course, Capabilities of Diagnostics, Treatment and Prevention in Adults and Children. Current Pediatrics. 2020; 19 (2): 123–31 (in Russ.)]. https://doi.org/10.15690/vsp.v19i2.2105
- Saccone G., Carbone F., Zullo F. The novel Coronavirus (2019- nCoV) in pregnancy: what we need to know. Eur J Obstet Gynecol Reprod Biol. 2020; 249: 92–3. DOI: 10.1016/j.ejogrb.2020.04.006
- Qiancheng X., Jian S., Lingling P. et al. Coronavirus disease 2019 in pregnancy. Int J Infect Dis. 2020; 95: 376–83. DOI: 10.1016/j.ijid.2020.04.065
- Chen L., Li Q., Zheng D. et al. Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China. N Engl J Med. 2020; 382 (25): e100. DOI: 10.1056/NEJMc2009226
- Mullins E., Evans D., Viner R.M. et al. Coronavirus in pregnancy and delivery: rapid review. Ultrasound Obstet Gynecol. 2020; 55 (5): 586–92. DOI: 10.1002/uog.22014
- Yan J., Guo J., Fan C. et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020; 223 (1): 111.e1–111.e14. DOI: 10.1016/j.ajog.2020.04.014