Current approaches to managing patients with acute liver failure

DOI: https://doi.org/10.29296/25877305-2020-02-16
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Issue: 
2
Year: 
2020

Professor O. Burgasova, MD; V. Tetova, Candidate of Medical Sciences Peoples’ Friendship University of Russia, Moscow

The paper considers data on the etiopathogenesis and clinical manifestations of acute liver failure (ARF), as well as current approaches to managing patients with this condition. Despite success in intensive care, ARF is a clinical syndrome with a high mortality rate that amounts to as much as 50%. The clinical picture is most frequently represented by the development of coagulopathy, encephalopathy, and multiple organ dysfunction. The severity of the course, the likelihood of irreversibility of RF, and the etiological heterogeneity of the syndrome necessitate further elaboration of therapeutic strategies.
Keywords: 
гепатология
печеночная недостаточность
печеночная энцефалопатия
этиопатогенез
вирусы
гепатотоксичность
лечение

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