Correction of involutional skin changes (a new neofibrolifting procedure)

DOI: https://doi.org/10.29296/25877305-2019-07-06
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Issue: 
7
Year: 
2019

A. Tsepkolenko(1), Candidate of Medical Sciences; Professor V. Tsepkolenko(1), MD; A. Mishra(2); A. Melerzanov(2), Candidate of Medical Sciences 1-Virtus Clinic, Odessa, Ukraine 2-Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region

Neofibrolifting is the use of autologous fibroblast transplantation in combination with preliminary skin preparation with platelet-rich plasma. This is an effective method for correcting involutional, age-related skin changes.
Keywords: 
dermatology
neofibrolifting
autologous fibroblasts
correction of skin aging manifestations

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References: 
  1. Zorina A.I., Zorin V.L., Cherkasov V.R. i dr. Kletochnye tehnologii v esteticheskoj meditsine // Sovremennye problemy dermatovenerologii, immunologii i vrachebnoj kosmetologii. – 2010; 4 (4): 76–82 [Zorina A.I., Zorin V.L., Cherkasov V.R. et al. Kletochnye tekhnologii v esteticheskoi meditsine // Sovremennye problemy dermatovenerologii, immunologii i vrachebnoi kosmetologii. – 2010; 4 (4): 76–82 (in Russ.)].
  2. Logina A.V., Supil'nikov A.A., Antipov E.V. Obzor metodov vozdejstvija na mikrotsirkuljatsiju kozhi // Vestnik meditsinskogo instituta «Reaviz»: Reabilitatsija, vrach i zdorov'e. – 2015; 3 (19): 57–61 [Logina A.V., Supil’nikov A.A., Antipov E.V. A review of methods influencing to skin microcirculation // Vestnik meditsinskogo instituta «Reaviz»: Reabilitatsiya, vrach i zdorov’e. – 2015; 3 (19): 57–61 (in Russ.)].
  3. Panchenko D.S., Kirgizova O.Ju. Rezul'taty morfofunktsional'nyh issledovanij suhoj kozhi litsa u zhenschin v raznyh vozrastnyh gruppah // Acta Biomedical Scientifica. – 2017; 2 (4): 32–8 [Panchenko D.S., Kirgizova O.Y. Results of the research of morphofunctional parameters of dry skin in women in different age groups // Acta Biomedica Scientifica. – 2017; 2 (4): 32–8 (in Russ.)]. https://doi.org/10.12737/article_59fad5113b9748.75608807.
  4. Sonis A.G., Sefedinova M.Ju., Bezrukova M.A. i dr. Primenenie obogaschennoj trombotsitami autoplazmy v lechenii patsientov s gnojno-vospalitel'nymi zabolevanijami mjagkih tkanej, kostej i sustavov // Aspirantskij vestnik Povolzh'ja. – 2016; 5–6: 162–7 [Sonis A.G., Sefedinova M.Y., Bezrukova M.A. et al. The use of platelet-rich autoplasma in the treatment of patients with pyoinflammatory diseases of soft tissues, bones and joints // Aspirantskii vestnik Povolzh’ya. – 2016; 5–6: 162–7 (in Russ.)].
  5. Hodzhaeva M.H., Isaeva M.S., Saidmuradova R.A. Endotelij sosudov i mehanizmy ego disfunktsii // Zdravoohranenie Tadzhikistana. – 2014; 2 (321): 77–86 [Hodgaeva M.H., Isaeva M.S., Saidmuradova R.A. The vascular endothelium and mehanisms of its dysfhunction // Zdravookhranenie Tadzhikistana. – 2014; 2 (321): 77–86 (in Russ.)].
  6. Tsepkolenko V.A. Kliniko-patogeneticheskoe obosnovanie differentsirovannogo podhoda k korrektsii involjutsionno-distroficheskih izmenenij kozhi // Vestn. estetich. meditsiny. – 2008; 7 (1): 28–33 [Tsepkolenko V.A. Kliniko-patogeneticheskoe obosnovanie differentsirovannogo podkhoda k korrektsii involyutsionno-distroficheskikh izmenenii kozhi // Vestnik esteticheskoi meditsiny. – 2008; 7 (1): 28–33 (in Russ.)].
  7. Tsepkolenko V.A. Sovremennaja kontseptsija korrektsii starenija kozhi // Vestn. estetich. meditsiny. – 2014; 13 (1): 12–9 [Tsepkolenko V.A. Modern conception of skin aging correction // Vestnik esteticheskoi meditsiny. – 2014; 13 (1): 12–9 (in Russ.)].
  8. Tsepkolenko V.A., Surovjak P. PRP-stimuljatsija sinteza kollagena I tipa v kozhe cheloveka: platsebokontroliruemoe issledovanie in vivo // Vestnik esteticheskoj meditsiny. – 2012; 11 (3): 17–24 [(in Russ.)]
  9. Bavik C., Coleman I., Dean J. et al. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms // Cancer Res. – 2006; 66: 794–802.
  10. Coppé J., Patil C., Rodier F. et al. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor // PLoS Biol. – 2008; 6: 2853–68.
  11. Cristofalo V., Allen R., Pignolo R. et al. Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation // Proc. Natl. Acad. Sci. USA. – 1998; 95 (18): 10614–9.
  12. De Luca C., Mikhal’chik E., Suprun M. et al. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study // Oxid. Med. Cell. Longev. – 2016; 2016: 4389410. DOI: 10.1155/2016/4389410.
  13. Fisher G., Quan T., Purohit T. et al. Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin // Am. J. Pathol. – 2009; 174 (1): 101–14. DOI: 10.2353/ajpath.2009.080599.
  14. Haniffa M., Ginhoux F., Wang X.-N. et al. Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation // J. Exp. Med. – 2009; 206 (2): 371–85. DOI: 10.1084/jem.20081633.
  15. Kuilman T., Peeper D. Senescence-messaging secretome: SMS-ing cellular stress // Nat. Rev. Cancer. – 2009; 9: 81–94.
  16. Lu S., Chang K., Liu C. et al. Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte // Carcinogenesis. – 2006; 27: 1273–84.
  17. Palmieri D., Watson J., Rinehart C. Age-related expression of PEDF/EPC-1 in human endometrial stromal fibroblasts: implications for interactive senescence // Exp. Cell Res. – 1999; 247: 142–7.
  18. Robinson J., Darzynkiewicz Z., Hyun W. et al. Current protocols in cytometry / New York: John Wiley & Sons, 2004.
  19. Sandby-Møller J., Poulsen T., Wulf H. Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits // ActaDermVenereol. – 2003; 83 (6): 410–3.
  20. Shao M., Zhu Y., Qiu Y. et al. Changes in the Level of Immunoglobulins and CD4/CD8 Ratio in Young and Aged Mice with Estradiol Deficiency // Immunol. Invest. – 2017; 46 (3): 305–13. DOI: 10.1080/08820139.2016.1267203.
  21. Sorrell J., Caplan A. Fibroblasts-a diverse population at the center of it all // Int. Rev. Cell Mol. Biol. – 2009; 276: 161–214. DOI: 10.1016/S1937-6448(09)76004-6.
  22. Stewart S., Stewart S. Immunophenotyping // Curr. Protoc. Cytom. – 2001; 6 (6.2): DOI: 10.1002/0471142956.cy0602s00.
  23. Tu W., Rao S. Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection // Front Microbiol. – 2016; 7: 2111. DOI: 10.3389/fmicb.2016.02111.
  24. Varani J., Dame M., Rittie L. et al. Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation // Am. J. Pathol. – 2006; 168 (6): 1861–8.
  25. Xie J., Zhang J., Wu H. et al. The influences of age on T lymphocyte subsets in C57BL/6 mice // Saudi J. Biol. Sci. – 2017; 24 (1): 108–13. DOI: 10.1016/j.sjbs.2016.09.002.
  26. Xue W., Zender L., Miething C. et al. Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas // Nature. – 2007; 445: 656–60.
  27. Zufferey A., Schvartz D., Nolli S. et al. Characterization of the platelet granule proteome: evidence of the presence of MHC1 in alpha-granules // J. Proteomics. – 2014; 101: 130–40. DOI: 10.1016/j.jprot.2014.02.008.