COSTA ACROKERATOELASTOIDOSIS: A RARE CASE

DOI: https://doi.org/10.29296/25877305-2019-03-11
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Issue: 
3
Year: 
2019

M. Tlish, MD; N. Sycheva, Candidate of Medical Sciences; M. Kartashevskaya, Candidate of Medical Sciences; M. Shavilova; F. Psavok, Candidate of Medical Sciences Kuban State Medical University, Krasnodar

The paper considers the etiopathogenetic factors of Costa acrokeratoelastoidosis that is a type of focal palmoplantar keratoderma with predominantly autosomal dominant inheritance and is accompanied by an elastic tissue lesion. It gives clinical and morphological criteria for verifying this pathology: childhood or adolescence diseases; focal palmoplantar keratoderma that is manifested by thickening of the stratum corneum of the palms and soles, by multiple ochroleucous horny papules, hyperhidrosis, as well as by histological changes characteristic of Costa acrokeratoelastoidosis (hyperkeratosis, acanthosis, granulosis of the epidermis and elastorrhexis) in the reticular dermis. The paper describes a rare sporadic case of non-hereditary Costa acrokeratoelastodosis. Its differential diagnosis is performed with focal acral hyperkeratosis and Devergie’s disease. The authors show the important diagnostic role of a histopathological examination of papular elements with the mandatory use of histochemical staining of elastic fibers

Keywords: 
dermatology
Costa acrokeratoelastoidosis
keratoderma
clinical and morphological criteria



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