Combination therapy for polyneuropathy in patients with type 2 diabetes mellitus

DOI: https://doi.org/10.29296/25877305-2018-09-08
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Issue: 
9
Year: 
2018

I. Pashkova; T. Potupchik, Candidate of Medical Sciences; M. Petrova, MD; O. Veselova, Candidate of Medical Sciences; I. Gatskikh, Candidate of Medical Sciences; T. Shalda Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

The paper provides an overview of the use of metabolic drug сocarnit in patients with diabetic polyneuropathy (DPNP). It considers the pathogenesis of DPNP in light of the development of oxidative stress in diabetes mellitus and the effect of medicines that are contained in сocarnit on its manifestation.
Keywords: 
endocrinology
diabetes mellitus
diabetic polyneuropathy
oxidative stress

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References: 
  1. Algoritmy spetsializirovannoj meditsinskoj pomoschi bol'nym saharnym diabetom. Pod red. Dedova I.I., M.V. Shestakovoj / M.: FGBU ENTs, 2013.
  2. Vertkin A.L., Danilov A.B., Mkrtumjan A.M. Konsensus po vedeniju bol'nyh s diabeticheskoj nejropatiej v obschej vrachebnoj praktike (utv. Sovetom ekspertov 8 aprelja 2017 g.) // Ambulatornyj priem. – 2017; 2 (8): 32–6.
  3. Vorob'eva O.V. Distal'naja diabeticheskaja polinejropatija: klinicheskie podtipy // Med. alfavit. – 2016; 8: 34–9.
  4. Vudu L., Parpauts K., Tkachenko O. Effektivnost' preparata Kokarnit v lechenii distal'noj polinejropatii u patsientov s saharnym diabetom 2-go tipa. URL: http:// www.worldmedicine.ru/?page_id=1154
  5. Gatskih I.V., Brikman I.N., Gazenkampf K.A. i dr. Dinamika nevrologicheskih narushenij na fone kombinirovannoj terapii u bol'nyh saharnym diabetom 2go tipa // Zhurnal nevrol. i psihiat. im. C.C. Korsakova. – 2018; 118 (6): 31–6.
  6. Devlikamova F.I. Primenenie preparata kokarnit pri lechenii patsientov s diabeticheskoj polinejropatiej // Zhurnal nevrol. i psihiat. im. S.S. Korsakova. – 2016; 11: 64–8.
  7. Zhukova L., Gulamov A, Kuznetsov E. Kompleksnoe lechenie diabeticheskoj polinejropatii // Vrach. – 2015; 1: 21–4.
  8. Ziganshin A.U. Rol' retseptorov ATF (R2-retseptorov) v nervnoj sisteme // Nevrol. vestn. im. V.M. Behtereva. – 2005; 37 (1– 2): 45–53.
  9. Karakulova Ju.V., Filimonova T.A. Monitoring kliniko-nejrofiziologicheskih pokazatelej pri diabeticheskoj polinejropatii v protsesse metabolicheskoj terapii // Doktor.ru. – 2017; 1 (130): 25–9.
  10. Klinicheskie rekomendatsii po nevrologii Evropejskoj federatsii nevrologicheskih soobschestv. Pod red. Gilhus N.E., Barnes M.P., Brainin M. / M.: OOO «ID «ABV-press»; 2012.
  11. Kotov S.V., Rudakova I.G. Diabeticheskaja polinejropatija: ot patogeneza k lecheniju i profilaktike // Al'manah klin. med. – 2016; 44 (3): 7–12.
  12. Litvinenko L.A., Korolenko G.G. Ispol'zovanie Kokarnita v kompleksnom lechenii diabeticheskoj polinejropatii // Med. novosti. – 2009; 3: 67–8.
  13. Mkrtumjan A.M., Markova T.N., Podachina S.V. Vozmozhnost' primenenija preparata Kokarnit pri lechenii diabeticheskoj polinejropatii // Endokrinologija. – 2016; 4: 6–10.
  14. Mkrtumjan A.M., Podachina S.V., Doskina E.V. i dr. Effektivnoe lechenie diabeticheskojnejropatii kompleksnym preparatom Kokarnit // Effektivnaja farmakoter. Endokrinologija. – 2015; 5 (43): 44–50.
  15. Nedosugova L.V. Vozmozhnosti medikamentoznoj korrektsii diabeticheskoj polinejropatii // Effektivnaja farmakoter. – 2016; 4: 46–52.
  16. Parfenov V.A., Golovacheva V.A., Fadeev V.V. i dr. Optimizatsija vedenija patsientov s diabeticheskoj polinejropatiej s pomosch'ju mezhdistsiplinarnogo podhoda // Nevrologija. – 2017; 5 (38): 71–9.
  17. Rachin A.P., Sharov M.N. Sravnitel'noe otkrytoe randomizirovannoe issledovanie po otsenke effektivnosti i bezopasnosti primenenija preparata Kokarnit pri boli v spine u patsientov, stradajuschih diabeticheskoj polinejropatiej // RMZh. – 2017; 9: 586–90.
  18. Strokov I.A., Fokina A.S., Strokov K.I. i dr. Sovremennye printsipy diagnostiki i lechenija diabeticheskoj polinejropatii // Med. sovet. – 2014; 5: 38–43.
  19. Sovremennye printsipy diagnostiki i lechenija diabeticheskoj polinejropatii // Med. sovet. – 2014; 5: 38–42.
  20. Hovasova N.O., Naumov A.V., Magomedova A.Ju. i dr. Diabeticheskaja nejropatija: chto dolzhen znat' terapevt polikliniki // Ambulatornyj priem. – 2016; 2 (5): 60–3.
  21. Shih E., Kukes V., Petunina N. Kokarnit: anal'geticheskij potentsial v lechenii polinejropatii // Vrach. – 2016; 4: 20–6.
  22. Ajjan R., Grant P. Cardiovascular disease prevention in patients with type 2 diabetes: The role of oral anti-diabetic agents // Diab. Vasc. Dis. Res. – 2006; 3 (3): 147–58.
  23. Arora S., Lidor A., Abularrage C. et al. Thiamine (vitamin B1) improves endotheliumdependent vasodilatation in the presence of hyperglycemia // Ann. Vasc. Surg. – 2006; 20 (5): 653–8.
  24. Burnstock G., Nistri A., Khakh B. et al. ATP-gated P2X receptors in health and disease // Front Cell Neurosci. – 2014; 8: 204.
  25. Callaghan B., Little A., Feldman E. et al. Enhanced glucose control for preventing and treating diabetic neuropathy // Cochrane Database Syst. Rev. – 2012; 6: CD007543.
  26. Callaghan B., Cheng H., Stables C. et al. Diabetic neuropathy: clinical manifestations and current treatments // Lancet. Neurol. – 2012; 11 (6): 521–34.
  27. DCCT Research Group. The effect of intensive diabetes therapy on the development and progression of neuropathy // Ann. Intern. Med. – 1995; 122 (8): 561–8.
  28. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group // Lancet. – 1998; 352 (91310): 837–53.
  29. Feng Y., Shan M., Bo L. et al. Association of homocysteine with type 1 diabetes mellitus: a meta-analysis // Int. J. Clin. Exp. Med. – 2015; 8 (8): 12529–38.
  30. Gazzaruso C., Coppol A., Montalcini T. et al. Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus // Endocrine. – 2012; 41 (1): 89–95.
  31. González R., Pedro T., Martinez-Hervas S. et al. Plasma homocysteine levels are independently associated with the severity of peripheral polyneuropathy in type 2 diabetic subjects // J. Peripher. Nerv. Syst. – 2012; 17 (2): 191–6.
  32. Ziegler D. Sovremennye printsipy vedenija bol'nyh s diabeticheskoj polinejropatiej // Nervno-myshechnye bolezni. – 2012; 2: 7–19.
  33. Wong C., Qiuwaxi J., Chen H. et al. Daily intake of thiamine correlates with the circulating level of endothelial progenitor cells and the endothelial function in patients with type II diabetes // Mol. Nutr. Food Res. – 2008; 52 (12): 1421–7.