FLUPIRTINE IN THE THERAPY OF CHRONIC LOW BACK PAIN SYNDROMES

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Issue: 
10
Year: 
2017

I. Vyshlova, Candidate of Medical Sciences; Professor S. Karpov, MD; A. Baida, MD Stavropol State Medical University

The use of flupirtine in chronic low back pain contributed to less pain intensity with a significant decrease in the levels of anxiety and depression and with better quality of life in patients.
Keywords: 
neurology
chronic low back pain syndrome
exacerbation
lumbodynia
flupirtine
treatment

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References: 
  1. Vyshlova I., Azoidis I., Karpov S. Epidemiology of vertebrogenic pain syndromes P12089 // Eur. J. Neurol. – 2016; 23 (S2): 293.
  2. Vyshlova I.A., Karpov S.M., Starodubtsev A.I. Vertebrogennye bolevye sindromy pojasnichnogo urovnja: epidemiologija, klinicheskie projavlenija // Med. vestn. Severnogo Kavkaza. – 2016; 11 (4): 586–8.
  3. Vyshlova I.A., Karpov S.M. Prichiny i ishody hronicheskogo bolevogo sindroma v nizhnej chasti spiny // Anesteziol. i reanimatol. – 2016; 61 (5S): 48.
  4. Vyshlova I.A. Kompleksnoe lechenie bol'nyh s hronicheskimi vertebrogennymi bolevymi sindromami // Kubanskij nauchn. med. vestnik. – 2012; 2: 47–9.
  5. Hronicheskaja bol' v spine. Klinicheskie rekomendatsii. Pod red. I.N. Denisova / M., SPb, Rostov-na-Donu, 2014; 20 s.
  6. Uberall M., Essner U., Müller-Schwefe G. 2-week efficacy and tolerability of flupirtine MR and diclofenac in patients with acute low/back pain--results of a post-hoc subgroup analysis of patient-level data from four non-interventional studies // MMW Fortschr. Med. – 2013; 155 (Suppl. 4): 115–23. German.
  7. Uberall M., Mueller-Schwefe G., Terhaag B. Efficacy and safety of flupirtine modified release for the management of moderate to severe chronic low back pain: results of SUPREME, a prospective randomized, double-blind, placebo- and active-controlled parallel-group phase IV study // Curr. Med. Res. Opin. – 2012; 28 (10): 1617–34. DOI: 10.1185/03007995.2012.726216.
  8. Pavlenko S., Veretel'nikov I., Fomin G. et al. The use of katadolon (flupirtine) in the treatment of lower back pain // Zh. Nevrol. Psikhiatr. im. S.S. Korsakova. – 2006; 106 (4): 70–1.
  9. Müller-Schwefe G., Uberall M. Analgesic and muscle tonus normalizing effect of flupirtine retard in chronic back pain // MMW Fortschr. Med. – 2007; 149 (43): 47.
  10. Li C., Ni J., Wang Z. et al. Analgesic efficacy and tolerability of flupirtine vs. tramadol in patients with subacute low back pain: a double-blind multicentre trial // Curr. Med. Res. Opin. – 2008; 24 (12): 3523–30. DOI: 10.1185/03007990802579769.