THYROID FUNCTION IN PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS

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Issue: 
8
Year: 
2017

Professor R. Abdullaev (1), MD; Professor O. Komissarova (1, 3), MD; E. Chumakova (2); V. Odinets (2) 1-Central Research Institute of Tuberculosis, Moscow 2-Territorial Clinical Tuberculosis Dispensary, Stavropol 3-N.I. Pirogov Russian National Research Medical University, Moscow

Patients with new-onset multidrug-resistant tuberculosis treated with ethionamide/protionamide and para-aminosalicylic acid were noted to have manifestations of hypothyroidism, which were especially pronounced after 4 and 5 months of therapy.
Keywords: 
phthisiology
multidrug-resistant tuberculosis
thyroid

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References: 
  1. Abdullaev R.Ju., Komissarova O.G., Chumakova E.S. i dr. Monitoring chastoty gepatotoksicheskih reaktsij v protsesse lechenija bol'nyh vpervye vyjavlennym MLU tuberkulezom legkih s ishodnymi narushenijami funktsii pecheni // Infektsionnye bolezni. – 2016; 14 (Pril. 1): 2.
  2. VOZ. Informatsionnyj bjulleten'. Oktjabr' 2016 g. [Elektronnyj resurs]: http://www.who.int/mediacentre/factsheets/fs104/ru/
  3. Dedov I.I. Endokrinologija / M.: Meditsina, 2000; 632 s.
  4. Egorova I.L. Znachenie endokrinnogo statusa v techenii i ishode tuberkuleza legkih. Avtoref. dis. … d-ra med. nauk. M., 1999; 46 s.
  5. Klinicheskoe rukovodstvo po laboratornym testam. Pod red. N. Titsa / M.: JuNIMED-press, 2003; 960 s.
  6. Klinicheskaja endokrinologija. Rukovodstvo. Pod red. N.T. Starkovoj. 3-e izd., pererab. i dop. / SPb: Sputnik vracha, 2002; 576 s.
  7. Komissarova O.G., Konjaeva O.O., Berezhnaja O.O. i dr. Effektivnost' lechenija bol'nyh tuberkulezom legkih s mnozhestvennoj i shirokoj lekarstvennoj ustojchivost'ju vozbuditelja v sochetanii s raznymi tipami saharnogo diabeta // Vestnik RGMU. – 2015; 3: 33–7.
  8. Livchane E. Lekarstvennaja neperenosimost', metody ee diagnostiki i korrektsii pri lechenii bol'nyh tuberkulezom legkih protivotuberkuleznymi preparatami rezervnogo rjada. Avtoref. dis. … kand. med. nauk. M., 2003; 22 s.
  9. Nechaeva O.B. Predvaritel'nye rezul'taty epidemiologicheskih pokazatelej po tuberkulezu za 2015 god. [El. resurs] // FGBU «TsNIIOIZ» Minzdrava Rossii [Ofits. sajt]. Elektronnyj resurs: http://www.mednet.ru/ru/czentr-monitoringa-tuberkuleza.html
  10. Skudarnova I.M., Soboleva N.V., Mychka N.V. Gormony schitovidnoj zhelezy: posobie dlja vrachej / Kol'tsovo: Vektor-Best, 2006; 32 s.
  11. Tereschenko I.V. Patogenez, diagnostika i lechenie subklinicheskogo gipotireoza // Klin. med. – 2000; 9: 8–13.
  12. Federal'nye klinicheskie rekomendatsii po diagnostike i lecheniju tuberkuleza organov dyhanija s mnozhestvennoj i shirokoj lekarstvennoj ustojchivost'ju vozbuditelja ot 28 maja 2015 g. M., 2015; 63 s. [Elektronnyj resurs] http://roftb.ru/netcat_files/doks2015/rec2.pdf
  13. Becks G., Eggo M., Burrow G. Organic iodine inhibits deoxyribonucleic acid synthesis and growth in FRTL-5 thyroid cells // Endocrinology. – 1988; 123: 545–51.
  14. Furin J., Mitnick C., Shin S. et al. Occurrence of serious adverse effects in patients receiving community-based therapy for multidrug-resistant tuberculosis // Int. J. Tuberc. Lung. Dis. – 2001; 5: 648–55.
  15. Ige O., Akinlade K., Rahamon S. et al. Thyroid function in multidrug-resistant tuberculosis patients with or without human immunodeficiency virus (HIV) infection before commencement of MDR-TB drug regimen // African Health Sci. – 2016; 16: 596–602.
  16. Kosack C., Page A.-L., Van Hulsteijn L. et al. TSH-CHECK-1 Test: Diagnostic Accuracy and Potential Application to Initiating Treatment for Hypothyroidism in Patients on Anti-Tuberculosis Drugs // PLoS ONE. – 2012; 7: e33704.
  17. Munkner T. Studies on goitre due to para-aminosalicylic acid // Scand. J. Respir. Dis. – 1996; 50: 212–26.
  18. Nathanson E., Gupta R., Huamani P. et al. Adverse events in the treatment of multidrug-resistant tuberculosis: results from the DOTS-Plus initiative // Int. J. Tuberc. Lung. Dis. – 2004; 8 (11): 1382–4.
  19. Sajid K., Parveen R., Sabih D. et al. Thyroid function in pulmonary tuberculosis // J. Coll. Physicians Surg. Pak. – 2006; 16 (10): 633–6.