DIFFICULT-TO-TREAT ASTHMA IN CHILDREN

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Issue: 
2
Year: 
2017

S. Dyakova, Candidate of Medical Sciences; N. Lev, Candidate of Medical Sciences; M. Kostyuchenko, Candidate of Medical Sciences; Professor Yu. Mizernitsky, MD; Professor N. Rozinova, MD Acad. Yu.E. Veltishchev Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow

A clinical example is used to discuss criteria for distinguishing difficult-to-treat asthma from severe asthma in children, to demonstrate different ways of complex monitoring of asthmatic children for the assessment of control over disease course: dynamic assessment of asthma control test values, spirometric data, and nitric oxide and carbon monoxide levels in exhaled air; regular audit of compliance with elimination measures, basic therapy, and inhalation techniques; smoking cessation; and consideration of comorbidities.

Keywords: 
pulmonology
asthma
children
compliance
control
monitoring
nitric oxide
carbon monoxide



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References: 
  1. GINA Report, Global Strategy for Asthma Management and Prevention. PublishedNovember 2016. http://www.ginasthma.org
  2. Bronhial'naja astma u detej: strategija lechenija i profilaktika. – Natsional'naja programma (5-e izd.) / M., 2017; 132 s.
  3. Belevskij A.S. Pravil'naja otsenka kontrolja zabolevanija – objazatel'noe uslovie adekvatnoj terapii bronhial'noj astmy // Atmosfera. Pul'monol. i allergol. – 2007; 1: 25–9.
  4. Demko I.V., Sobko E.A., Kraposhina A.Ju. i dr. Uroven' kontrolja u bol'nyh bronhial'noj astmoj v klinicheskoj praktike // Pul'monologija. – 2011; 4: 76–9.
  5. Chernjak B.A., Vorzheva I.I. Kontroliruemoe techenie bronhial'noj astmy kak osnovnaja tsel' terapii v povsednevnoj klinicheskoj praktike // Atmosfera. Pul'monol. i allergol. – 2008; 2: 34–8.
  6. Voorend van Bergen S., Vaessen-Verberne A., Brackel H. et al. Monitoring strategies in children with asthma: a randomized controlled trial // Thorax. – 2015; 70: 543–50.
  7. Ahverdieva M.K., Katel'nitskaja L.I., Kolmakova T.S. i dr. Puti optimizatsii antismokingovoj politiki v molodezhnoj srede. V kn.: Materialy Vserossijskoj nauchnoj konferentsii «Aktual'nye problemy profilaktiki neinfektsionnyh zabolevanij» / M., 1999; 2: 4.
  8. Tsyplenkova S.E., Mizernitskij Ju.L. Klinicheskoe znachenie opredelenija oksida azota v vydyhaemom vozduhe pri zabolevanijah legkih u detej // Ros. vestn. perinatol. i pediat. – 2005; 6 (50): 16–21.
  9. Tsyplenkova S.E., Mizernitskij Ju.L. Oksid azota v vydyhaemom vozduhe: kliniko-funktsional'nye paralleli pri bronhial'noj astme u detej // Allergologija. – 2006; 2: 48–53.
  10. Majid H., Kao C. Utility of exhaled nitric oxide in the diagnosis and management of asthma // Curr. Opin. Pulm. Med. – 2010; 16 (1): 42–7.
  11. Van Veen I., Ten Brinke A., Sterk P. et al. Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma // Eur. Respir. J. – 2008; 32: 344–9.
  12. Tsyplenkova S.E., Mizernitskij Ju.L., Sokolova L.V. i dr. Omalizumab: innovatsionnyj podhod k terapii nekontroliruemoj tjazheloj bronhial'noj astmy i komorbidnyh zabolevanij u detej // Ros. allergol. zhurn. – 2014; 5: 57–60.
  13. Tsyplenkova S.E., Mizernitskij Ju.L., Sokolova L.V. i dr. Novye vozmozhnosti kontrolja effektivnosti anti-IgE-terapii pri tjazheloj bronhial'noj astme u detej // Ros. vestn. perinatol. i pediat. – 2013; 3 (58): 47–54.