HEARTBURN IN PREGNANT WOMEN: SAFE TREATMENT

Download full text PDF
Issue: 
10
Year: 
2016

Professor E. Eremina, MD N.P. Ogarev Mordovia State Medical University, Saransk

The paper presents the basic mechanisms of heartburn and its drug therapy policy in pregnant women. It emphasizes the role of gastroesophageal reflux and an association of heartburn in pregnancy with the subsequent development of gastroesophageal reflux disease.
Keywords: 
gastroenterology
heartburn
pregnancy
gastroesophageal reflux disease
alginates

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Rodriguez A., Bohlini G., Lindmark G. Symptoms across pregnancy in relation to psychosocial and biomedical factors // Acta Obstet. Gynecol. Scand. – 2001; 80: 213–23.
  2. Burkov S.G. Izzhoga beremennyh // Consilium Medicum. Ginekologija (Pril.). – 2004.
  3. Elohina T.B., Tjutjunnik V.L. Gastroezofageal'naja refljuksnaja bolezn' pri beremennosti // Eksperim. i klin. gastroenterol. – 2009; 3: 93–7.
  4. Onuchina E.V., Gorobets E.A., Rozhanskij A.A. i dr. Simptomy gastroezofa geal'noj refljuksnoj bolezni u beremennyh // Lechaschij vrach. – 2010; 2: 88–91.
  5. Ramu B., Mohan P., Rajasekaran M. et al. Prevalence and risk factors for gastroesophageal reflux in pregnancy // Indian J. Gastroenterol. – 2011; 30 (3): 144–7.
  6. Mandel K.G., Deggi B.P., Brodi D.A. i dr. Al'ginatsoderzhaschie prepara ty v lechenii gastroezofageal'noj refljuksnoj bolezni // Spravochnik poli-klinicheskogo vracha. – 2008; 10: 46–9.
  7. Ushkalova E.A. Lechenie gastroezofageal'nogo refljuksa u beremennyh zhenschin // Ginekologija. – 2001; 3: 89–90.
  8. Richter J. Gastroesophageal reflux disease during pregnancy // Gastroenterol. Clin. North. Am. – 2003; 32: 235–61.
  9. Bainbridge E. Symptomatic gastro-esophageal reflux in pregnancy: a comparative study of white Europeans and Asians in Birmingham // Br. J. Clin. Pract. – 2003; 37: 53–7.
  10. Fil S., Malfertheiner M., Costa S. D., Monkemuller K. Handling of the gastroesophageal reflux disease (GERD) during pregnancy-a review // Z. Geburtshilfe Neonatol. – 2007; 211: 215–23.
  11. Naumann C., Zelig C., Napolitano P. et al. Nausea, vomiting, and heartburn in pregnancy: a prospective look at risk, treatment, and outcome // J. Maternal-Fetal Neonatal. Med. – 2012; 25 (8): 1488–93.
  12. remina E.Ju., Masharova A.A. Zabolevanija organov pischevaritel'noj sistemy u beremennyh / Saransk, 2009; 200 s
  13. Lazebnik L.B., Masharova A.A., Tkachenko E.I. i dr. Mnogotsentrovoe issledovanie MEGRE: pervye itogi // Eksperim. i klin. gastroenterol. – 2009; 6: 4–12.
  14. Stanghellini V. Management of gastroesophageal reflux disease // Drugs 14. Today. – 2003; 39: 15–20.Rey E. Simptomy gastroezofageal'nogo refljuksa vo vremja i posle 15. beremennosti // Am. J. Gastroenterol. Russkoe izdanie. – 2008; 2: 1: 1–6.
  15. Bor S., Kitapcioglu G., Dettmar P. et al. Svjaz' mezhdu izzhogoj vo vremja beremennosti i riskom gastroezofageal'noj refljuksnoj bolezni // Klin. gastroenterol. i gepatol. Russkoe izdanie. – 2008; 6: 396–400.
  16. Uspenskij Ju.L., Baryshnikova N.B. Izzhoga i gastroezofageal'naja refljuksnaja bolezn' u beremennyh: aktual'nost' ispol'zovanija al'ginatov // Lechaschij vrach. – 2012; 11: 17–20.
  17. Maev I.V., Dicheva D.T., Andreev D.N. i dr. Mesto al'ginatov v sovre mennyh algoritmah terapii gastroezofageal'noj refljuksnoj bolezni // Gastroenterologija. – 2012; 2: 12–7. Standarty diagnostiki i lechenija kislotozavisimyh i assotsiirovan-19. nyh s Nr zabolevanij (5-e Moskovskie soglashenija), 2015.
  18. McColl K., Clarke A., Seenan J. Acid pocket, hiatus hernia and acid reflux // Gut. – 2010; 59: 430–1.
  19. Scherbinina M.B., Morozova N.K. Geviskon forte – nadezhnyj pomosch nik v lechenii GERB. Novosti meditsiny i farmatsii // Gastroenterologija (tematicheskij nomer). – 2008: 239.
  20. Tran T., Lowry A., El-Serag H. Meta-analysis: the efficacy of over-the- counter gastro-oesophageal reflux disease drugs // Aliment. Pharmacol. Ther. – 2007; 25 (2): 143–53.
  21. Berthon G. Aluminium speciation in relation to aluminium bioavailability, metabolism and toxiety // Coord. Ghem. Rev. – 2002; 228: 319–41.
  22. Mahadevan U., Kane S. American gastroenterological association institute medical position statement on the use of gastrointestinal medications in pregnancy // Gastroenterology. – 2006; 131: 278–82.
  23. Uspenskij Ju.P., Baryshnikova N.V., Pahomova I.G. Klinicheskie per spektivy ispol'zovanija preparatov na osnove al'ginovoj kisloty v lechenii gastroezofageal'noj refljuksnoj bolezni // RZhGGK. – 2009; 19 (2): 79–84
  24. Bordin D.S., Masharova A.A., Firsova L.D. i dr. Otsenka skorosti dejstvija i kupirovanija izzhogi pri odnokratnom prieme al'ginatov u bol'nyh GERB // Eksper. i klin. gastroenterol. – 2009; 4: 83–91.
  25. Janczyk P., Pieper R., Smidt H. et al. Effect of alginate and inulin on 27. intestinal microbial ecology of weanling pigs reared under different husbandry conditions // FEMS Microbiol. Ecol. – 2010; 72 (1): 132–42.
  26. Lindou S., Regnell P., Sajke Dzh. i dr. Otkrytoe mnogotsentrovoe issledovanie po otsenke bezopasnosti i effektivnosti novogo sredstva ot izzhogi (Geviskon Forte®) vo vremja beremennosti // RMZh. – 2008; 6: 439
  27. Lazebnik L.B., Bordin D.S., Masharova A.A. i dr. Vosstanovlenie kache stva zhizni ustraneniem i predotvrascheniem izzhogi al'ginatom: rezul'taty mnogotsentrovogo issledovanija VIA APIA // Eksperim. i klin. gastroente-rol. – 2010; 6: 70–6.
  28. Strugala V., Dettmar P., Sarratt K. et al. A randomized, controlled, crossover 30. trial to investigate times to onset of the perception of soothing and cooling by over-the-counter heartburn treatments // J. Int. Med. Res. – 2010; 38: 449–57
  29. Rohof W., Bennink R., Boeckxstaens G. Effect of PPI on the size, position 31. and acidity of the postprandial acid pocket // Gastroenterology. – 2012; 124: 92.
  30. Mahov B.M., Turko T.V., Tarba K.S. Lechenie gastroezofageal'noj ref ljuksnoj bolezni – mnogofaktornyj podhod // Rus. med. zhurn. – 2013; 31: 3–6.
  31. Brigg G., Freeman R., Yaffe S. Drugs in pregnancy and lactation: a 33. referanceguide to fetal and neonatal risk / Baltimore: Williams and Wilkins, 2002.Instruktsija po meditsinskomu primeneniju preparata Geviskon®, 34. Geviskon® forte.