INTEGRATION OF THE EXTENT OF TUMOR LESION INTO A PROGNOSTIC MODEL OF HODGKIN LYMPHOMA
Issue:
11
Year:
2015
The fact that correlation and regression analysis can consider the volume of a tumor in children with Hodgkin lymphoma results in a change of its contribution to the long-term prognosis of other parameters, by creating prerequisites for improving prognostic models and stratifying patients into risk groups in terms of only this factor.
Keywords:
Hodgkin lymphoma
tumor lesion extent
prognostic model
References:
- Gobbi P., Comelli M., Grignani G. et al. Estimate of expected survival at diagnosis in Hodgkin's disease: a means of weighting prognostic factors and a tool for treatment choice and clinical research. A report from the International Database on Hodgkin's Disease (IDHD) // Haematologica. – 1994; 79: 241–55.
- Hasenclever D., Diehl V. A prognostic score to predict tumor control in advanced Hodgkin's disease // N. Engl. J. Med. – 1998; 339: 1506–14.
- Kolygin B.A., Lebedev S.V. Prognosticheskie faktory pri kompleksnom lechenii limfogranulematoza u detej. 2-j S'ezd detskih onkologov i gematologov Rossii: Tez. dokl. Rostov-na-Donu, 2001; s. 92–3.
- Specht L. Tumor burden as the main indicator of prognostic in Hodgkin’s disease // Eur. J. Cancer. – 1992; 28: 1982–5.
- Specht L., Nordentoft A., Cold S. et al. Tumor burden as the most important prognostic factor in early stage Hodgkin’s disease. Relations to other prognostic factors and implications for choice of treatment // Cancer. – 1988; 61: 1719–27.
- Gobbi P., Bergonzi M., Bassi E. et al. Tumor burden in Hodgkin’s lymphoma can be reliably estimated from a few staging parameters // Oncology reports. – 2012; 28: 815–20.
- Zweig M., Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine // Clin. Chemistry. – 1993; 39: 561–77.
- Junkerov V.I., Grigor'ev S.G., Rezvantsev M.V. Matematiko-statisticheskaja obrabotka dannyh meditsinskih issledovanij / SPb: VMedA, 2002; 266 s.
- Gobbi P., Broglia C., Giulio G. et al. The clinical value of tumor burden at diagnosis in Hodgkin lymphoma // Cancer. – 2000; 101: 1824–34.
- Kulyova S., Kolygin B. Hodgkin’s lymphoma in children and adolescents: a Saint Petersburg Hodgkin’s Lymphoma Group Study // J. Oncol. – 2011; Available at: http://dx.doi.org/10.1155/2011/958435