INTRA-CAVITY RONKOLEUKIN IMMUNOTHERAPY IN TREATMENT RESISTANT PATIENTS WITH MALIGNANT EFFUSIONS

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Issue: 
11
Year: 
2015

K. Titov (1), Candidate of Medical Sciences; Professor M. Kiselevsky (2), MD; I. Shubina (2), Doctor of Biological Sciences; Professor R. Izrailov (1), MD; N. Semenov (1) 1 -Moscow Clinical Research Centre 2 -N.N. Вlokhin Russian Сancer Research Centre, Moscow

The study evaluated feasibility, safety and effectiveness in combination with recombinant interleukin-2 (IL2) used for antitumor immunotherapy. The clinical study involved cancer patients with metastatic effusions resistant to systemic chemotherapy. The results showed that intra-cavity IL2-immunotherapy was highly effective and well tolerated in treatment of patients with malignant effusions.

Keywords: 
immunotherapy
metastatic effusions
interleukin-2



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