A MINIMALLY MANIPULATED CELLULAR PRODUCT IN PLASTIC SURGERY AND REGENERATIVE MEDICINE

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Issue: 
8
Year: 
2015

A. Melerzanov (1), Candidate of Medical Sciences; N. Manturova (2), MD 1 -Moscow Institute of Physics and Technology 2 -N.I. Pirogov Russian National Research Medical University, Moscow

The use of minimally manipulated cellular products in regenerative medicine and plastic surgery will open up fresh opportunities in the development of personalized medicine. Large plastic surgery clinics are mostly adapted to this type of medical care owing to the qualification of the staff and the possibilities of setting up laboratories to work with cellular products.

Keywords: 
minimally manipulated cellular products
adipose-derived stem cells
plastic surgery
regenerative medicine



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References: 
  1. Meyer J., Salamon A., Herzmann N. et al. Isolation and Differentiation Potential of Human Mesenchymal Stem Cells From Adipose Tissue Harvested by Water Jet-Assisted Liposuction // Aesthet. Surg. J. – 2015; pii: sjv075.
  2. Aleksandrova O.Ju., Melerzanov A.V. Problemy litsenzirovanija medi tsinskoj dejatel'nosti, svjazannoj s razrabotkoj i primeneniem kletochnyh tehnologij // Ekonomika zdravoohranenija. – 2010; 3 (147): 55–60
  3. Aleksandrova O.Ju., Melerzanov A.V. Organizatsionno-pravovye pro blemy razrabotki i primenenija novyh kletochnyh tehnologij v RF // Zdravoohranenie. – 2010; 5: 143–50.
  4. Aleksandrova O.Ju., Melerzanov A.V. Organizatsionno-pravovye problemy razrabotki i primenenija novyh kletochnyh tehnologij v RF (prodol-zhenie) // Zdravoohranenie. – 2010; 6: 155–72.
  5. Aleksandrova O.Ju., Melerzanov A.V. Organizatsionno-pravovye problemy razrabotki i primenenija novyh kletochnyh tehnologij v RF (okoncha-nie) // Zdravoohranenie. – 2010; 7: 149–60.
  6. Isaev A.A. O zakonoproekte «Ob obraschenii biomeditsinskih kletochnyh produktov» http://genescells.ru/blog/post/148
  7. Kabmin napravil v Gosdumu zakonoproekt ob obraschenii biomeditsin skih kletochnyh produktov. http://tass.ru/obschestvo/1748515
  8. Minimal Manipulation of Human Cells, Tissues, and Cellular and Tissue-8. Based Products: http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/CellularandGeneTherapy/ucm427692.htm
  9. Draft Guidance for Industry: Same Surgical Procedure Exception under 21 9. CFR 1271.15(b): Questions and Answers Regarding the Scope of the Exception http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/Tissue/ucm419911.htm
  10. Stem cell clinics, FDA, and giant, unapproved for-profit human experiments. http://www.ipscell.com/2015/01/stemhumanexperiment/
  11. Minteer D., Marra K., Rubin J. Adipose stem cells: biology, safety, regulation, and regenerative potential // Clin. Plast. Surg. – 2015; 42 (2): 169–79. doi: 10.1016/j.cps.2014.12.007
  12. Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/Ps) from Adipose Tissue: Regulatory Considerations; Draft Guidance http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/Tissue/ucm427795.htm
  13. Marino G., Moraci M., Armenia E. et al. Therapy with autologous adipose derived regenerative cells for the care of chronic ulcer of lower limbs in patients with peripheral arterial disease // J. Surg. Res. – 2013; 185 (1): 36–44. doi: 10.1016/j.jss.2013.05.024. Epub 2013 May 28.
  14. Prikaz Ministerstva zdravoohranenija RF ot 30 oktjabrja 2012 g. 14. №555n «Ob utverzhdenii Porjadka okazanija meditsinskoj pomoschi po profi-lju «plasticheskaja hirurgija»».