CAUSES OF POOR OUTCOMES IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME CONCURRENT WITH MULTIFOCAL ATHEROSCLEROSIS

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Issue: 
2
Year: 
2015

Professor S. Berns (1), MD; E. Shmidt (1), Candidate of Medical Sciences; A. Klimenkova (2), Candidate of Medical Sciences; O. Nagirnyak (1); S. Frolova (1); Professor O. Barbarash (1), MD; 1 -Research Institute for Complex Issues of Cardiovascular Diseases, Siberian Branch, Russian Academy of Medical Sciences, Kemerovo 2 -Kemerovo Cardiology Dispensary, Kemerovo

This study enrolled 149 patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), who were ascertained to have a high incidence of multifocal atherosclerosis. The poor predictors were found to include increased cardiac-ankle vascular index and statin therapy discontinuation after NSTE-ACS. The women are more frequently discharged from hospital with a diagnosis of unstable angina pectoris and have no atherosclerotic lesion in the coronary and peripheral arteries while the men more commonly develop non-Q-wave myocardial infarction and have multifocal injury in the vascular bed.

Keywords: 
non-ST-segment elevation acute coronary syndrome
multifocal atherosclerosis
prognosis



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References: 
  1. Kontsevaja A.V., Kalinina A.M., Koltunov I.E. i dr. Sotsial'no-ekonomicheskij uscherb ot ostrogo koronarnogo sindroma v Rossijskoj Federatsii // Rats. farmakoter. v kardiol. – 2011; 7 (2): 158–66.
  2. Oganov R.G. Dislipidemii i ateroskleroz. Biomarkery, diagnostika i lechenie: rukovodstvo dlja vrachej / M.: GEOTAR-Media, 2009; 160 s.
  3. Serdechno-sosudistye zabolevanija. Informatsionnyj bjulleten' № 3. 317 Vsemirnoj organizatsii zdravoohranenija, 2011.
  4. Ergina E.B. Serdechno-sosudistye zabolevanija – samaja chastaja prichina smerti v Rossii. Materialy trudov 1-j mezhdunarodnoj telekonferentsii «Problemy i perspektivy sovremennoj meditsiny, biologii i ekologii» // Fundamental'nye nauki i praktika. – 2010; 1 (1): 65–6.
  5. Poredos P. The prevalence of peripheral arterial in high risk subjects and 5. coronary or cerebrovascular patients // Angiology. – 2007; 3 (58): 309–15.
  6. Rigatelli G., Roncon L., Bedendo E. et al. Concomitant peripheral vascular 6. and coronary artery disease: a new dimension for the global endovascular specialist? // Clin. Cardiol. – 2005; 28: 231–5.
  7. Barbarash O.L., Zykov M.V., Kashtalap V.V. i dr. Rasprostranennost' i klinicheskaja znachimost' mul'tifokal'nogo ateroskleroza u patsientov s ishemicheskoj bolezn'ju serdtsa // Kardiologija. – 2011; 8: 66–71.
  8. Kuijk J., Flu W., Welten G. et al. Long-term prognosis of patients with peripheral arterial disease with or without polyvascular atherosclerotic disease // Eur. Heart J. – 2009; 32 (11): 992–9.
  9. But G. I s'ezd sosudistyh i endovaskuljarnyh hirurgov Ukrainy [Elektronnyj resurs] // Mezhdunarodnyj nevrologicheskij zhurnal. – 2006.; 6 (10): rezhim dostupa: http://www.mif-ua.com/archive/article/2345 (27.05.2013).
  10. The SYNTAX Score: an angiographic tool grading the complexity ofcoronary artery disease // Eurointervention. – 2005; 1: 219–27.
  11. Tavlueva E.V., Sin'kov M.A., Vasil'eva O.A. i dr. Gendernye osobennosti porazhenija koronarnogo rusla s ob'ektivizatsiej po shkale SYNTAX u bol'nyh infarktom miokarda s pod'emom segmenta ST // Patologija krovoo-braschenija i kardiohirurgija. – 2011; 1: 59–63.
  12. Wenger N., Collins P. Women’s and heart disease / N.Y.: Taylor and Francis, 12. 2005; p. 640.
  13. Sheifer S., Arora U., Gersh B. et al. Sex differences in morphology of 13. coronary artery plaque assessed by intravascular ultrasound // Coron. Artery Dis. – 2001; 12: 17–20.
  14. Cruickshank K., Riste L., Anderson S. et al. Aortic pulse-wave velocity and 14. its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function // Circulation. – 2002; 106: 2085–90.
  15. Satlykova D.F., Kechedzhieva N., Skvortsov A.A. i dr. Sravnitel'naja otsenka zhestkosti arterial'noj stenki u bol'nyh sistolicheskoj hroniche-skoj serdechnoj nedostatochnost'ju razlichnoj etiologii. Tez. III Kongressa (IX konferentsii) Obscherossijskoj obschestvennoj organizatsii. Obschestvo sptsialistov po serdechnoj nedostatochnosti «Serdechnaja nedostatochnost' 2008». M., 2008; s. 62.
  16. Matrosova I.B., Borisocheva I.V., Olejnikov V.E. Serdechno- lodyzhechnyj sosudistyj indeks (CAVI) – novyj neinvazivnyj parametr otsenki sosudistoj regidnosti // Meditsinskie nauki. Obzory literatury. – 2009; 2 (10): 90–101.
  17. Rogoza A.N. Rol' i vozmozhnosti lodyzhechno-plechevogo indeksa . sistolicheskogo davlenija pri profilakticheskih obsledovanijah // Rus. med. zhurn. – 2011; 4 (19): 173–9.
  18. Rizos E., Agouridis A., Elisaf M. The effect of statin therapy on arterial 18. stiffness by measuring pulse wave velocity: a systematic review // Curr. Vasc. Pharmacol. – 2010; 8 (5): 638–44.
  19. Meng X., Qie L., Wang Y. et al. Assessment of arterial stiffness affected by 19. atorvastatin in coronary artery disease using pulse wave velocity // Clin. Invest. Med. – 2009; 32 (6): 238.
  20. Miyashita Y., Endo K., Saiki A. et al. Effects of pitavastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardio-ankle vascular index in type 2 diabetic patients // J. Atheroscler. Thromb. – 2009; 16 (5): 539–45.